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A Quantitative Measure of Electrostatic Perturbation in Holo and Apo Enzymes Induced by Structural Changes
Biological pathways are subject to subtle manipulations that achieve a wide range of functional variation in differing physiological niches. In many instances, changes in the structure of an enzyme on ligand binding germinate electrostatic perturbations that form the basis of its changed catalytic o...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597595/ https://www.ncbi.nlm.nih.gov/pubmed/23516628 http://dx.doi.org/10.1371/journal.pone.0059352 |