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Bioengineered 3D Human Kidney Tissue, a Platform for the Determination of Nephrotoxicity

The staggering cost of bringing a drug to market coupled with the extremely high failure rate of prospective compounds in early phase clinical trials due to unexpected human toxicity makes it imperative that more relevant human models be developed to better predict drug toxicity. Drug–induced nephro...

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Detalles Bibliográficos
Autores principales: DesRochers, Teresa M., Suter, Laura, Roth, Adrian, Kaplan, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597621/
https://www.ncbi.nlm.nih.gov/pubmed/23516613
http://dx.doi.org/10.1371/journal.pone.0059219