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Bioengineered 3D Human Kidney Tissue, a Platform for the Determination of Nephrotoxicity
The staggering cost of bringing a drug to market coupled with the extremely high failure rate of prospective compounds in early phase clinical trials due to unexpected human toxicity makes it imperative that more relevant human models be developed to better predict drug toxicity. Drug–induced nephro...
Autores principales: | DesRochers, Teresa M., Suter, Laura, Roth, Adrian, Kaplan, David L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597621/ https://www.ncbi.nlm.nih.gov/pubmed/23516613 http://dx.doi.org/10.1371/journal.pone.0059219 |
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