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Creation of Lung-Targeted Dexamethasone Immunoliposome and Its Therapeutic Effect on Bleomycin-Induced Lung Injury in Rats

OBJECTIVE: Acute lung injury (ALI), is a major cause of morbidity and mortality, which is routinely treated with the administration of systemic glucocorticoids. The current study investigated the distribution and therapeutic effect of a dexamethasone(DXM)-loaded immunoliposome (NLP) functionalized w...

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Detalles Bibliográficos
Autores principales: Chen, Xue-Yuan, Wang, Shan-Mei, Li, Nan, Hu, Yang, Zhang, Yuan, Xu, Jin-Fu, Li, Xia, Ren, Jie, Su, Bo, Yuan, Wei-Zhong, Teng, Xin-Rong, Zhang, Rong-Xuan, Jiang, Dian-hua, Mulet, Xavier, Li, Hui-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597622/
https://www.ncbi.nlm.nih.gov/pubmed/23516459
http://dx.doi.org/10.1371/journal.pone.0058275