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(Pro)renin Receptor Mediates Both Angiotensin II-Dependent and -Independent Oxidative Stress in Neuronal Cells

The binding of renin or prorenin to the (pro)renin receptor (PRR) promotes angiotensin (Ang) II formation and mediates Ang II-independent signaling pathways. In the central nervous system (CNS), Ang II regulates blood pressure via inducing oxidative stress; however, the role of PRR-mediated Ang II-i...

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Detalles Bibliográficos
Autores principales: Peng, Hua, Li, Wencheng, Seth, Dale M., Nair, Anand R., Francis, Joseph, Feng, Yumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597628/
https://www.ncbi.nlm.nih.gov/pubmed/23516464
http://dx.doi.org/10.1371/journal.pone.0058339