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Connexin 30 Expression and Frequency of Connexin Heterogeneity in Astrocyte Gap Junction Plaques Increase with Age in the Rat Retina

We investigated age-associated changes in retinal astrocyte connexins (Cx) by assaying Cx numbers, plaque sizes, protein expression levels and heterogeneity of gap junctions utilizing six-marker immunohistochemistry (IHC). We compared Wistar rat retinal wholemounts in animals aged 3 (young adult), 9...

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Detalles Bibliográficos
Autores principales: Mansour, Hussein, McColm, Janet R., Cole, Louise, Weible, Michael, Korlimbinis, Anastasia, Chan-Ling, Tailoi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597639/
https://www.ncbi.nlm.nih.gov/pubmed/23516399
http://dx.doi.org/10.1371/journal.pone.0057038