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Physico-chemical foundations underpinning microarray and next-generation sequencing experiments

Hybridization of nucleic acids on solid surfaces is a key process involved in high-throughput technologies such as microarrays and, in some cases, next-generation sequencing (NGS). A physical understanding of the hybridization process helps to determine the accuracy of these technologies. The goal o...

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Detalles Bibliográficos
Autores principales: Harrison, Andrew, Binder, Hans, Buhot, Arnaud, Burden, Conrad J., Carlon, Enrico, Gibas, Cynthia, Gamble, Lara J., Halperin, Avraham, Hooyberghs, Jef, Kreil, David P., Levicky, Rastislav, Noble, Peter A., Ott, Albrecht, Pettitt, B. Montgomery, Tautz, Diethard, Pozhitkov, Alexander E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597649/
https://www.ncbi.nlm.nih.gov/pubmed/23307556
http://dx.doi.org/10.1093/nar/gks1358