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Widespread inference of weighted microRNA-mediated gene regulation in cancer transcriptome analysis

MicroRNAs (miRNAs) comprise a gene-regulatory network through sequence complementarity with target mRNAs. Previous studies have shown that mammalian miRNAs decrease many target mRNA levels and reduce protein production predominantly by target mRNA destabilization. However, it has not yet been fully...

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Detalles Bibliográficos
Autores principales: Suzuki, Hiroshi I., Mihira, Hajime, Watabe, Tetsuro, Sugimoto, Koichi, Miyazono, Kohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597654/
https://www.ncbi.nlm.nih.gov/pubmed/23275554
http://dx.doi.org/10.1093/nar/gks1439