Histone methyltransferase SETD2 coordinates FACT recruitment with nucleosome dynamics during transcription

Histone H3 of nucleosomes positioned on active genes is trimethylated at Lys36 (H3K36me3) by the SETD2 (also termed KMT3A/SET2 or HYPB) methyltransferase. Previous studies in yeast indicated that H3K36me3 prevents spurious intragenic transcription initiation through recruitment of a histone deacetyl...

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Detalles Bibliográficos
Autores principales: Carvalho, Sílvia, Raposo, Ana Cláudia, Martins, Filipa Batalha, Grosso, Ana Rita, Sridhara, Sreerama Chaitanya, Rino, José, Carmo-Fonseca, Maria, de Almeida, Sérgio Fernandes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597667/
https://www.ncbi.nlm.nih.gov/pubmed/23325844
http://dx.doi.org/10.1093/nar/gks1472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597667/
https://www.ncbi.nlm.nih.gov/pubmed/23325844
http://dx.doi.org/10.1093/nar/gks1472

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