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Histone methyltransferase SETD2 coordinates FACT recruitment with nucleosome dynamics during transcription
Histone H3 of nucleosomes positioned on active genes is trimethylated at Lys36 (H3K36me3) by the SETD2 (also termed KMT3A/SET2 or HYPB) methyltransferase. Previous studies in yeast indicated that H3K36me3 prevents spurious intragenic transcription initiation through recruitment of a histone deacetyl...
Autores principales: | Carvalho, Sílvia, Raposo, Ana Cláudia, Martins, Filipa Batalha, Grosso, Ana Rita, Sridhara, Sreerama Chaitanya, Rino, José, Carmo-Fonseca, Maria, de Almeida, Sérgio Fernandes |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597667/ https://www.ncbi.nlm.nih.gov/pubmed/23325844 http://dx.doi.org/10.1093/nar/gks1472 |
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