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Histone H4 Lysine 20 methylation: key player in epigenetic regulation of genomic integrity
Maintenance of genomic integrity is essential to ensure normal organismal development and to prevent diseases such as cancer. Nuclear DNA is packaged into chromatin, and thus genome maintenance can be influenced by distinct chromatin environments. In particular, post-translational modifications of h...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597678/ https://www.ncbi.nlm.nih.gov/pubmed/23345616 http://dx.doi.org/10.1093/nar/gkt012 |