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MCPIP1 ribonuclease exhibits broad-spectrum antiviral effects through viral RNA binding and degradation

Monocyte chemoattractant protein 1-induced protein 1 (MCPIP1), belonging to the MCPIP family with highly conserved CCCH-type zinc finger and Nedd4-BP1, YacP Nuclease domains, has been implicated in negative regulation of the cellular inflammatory responses. In this report, we demonstrate for the fir...

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Detalles Bibliográficos
Autores principales: Lin, Ren-Jye, Chien, Hsu-Ling, Lin, Shyr-Yi, Chang, Bi-Lan, Yu, Han-Pang, Tang, Wei-Chun, Lin, Yi-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597685/
https://www.ncbi.nlm.nih.gov/pubmed/23355615
http://dx.doi.org/10.1093/nar/gkt019