Mini-chromosome maintenance complexes form a filament to remodel DNA structure and topology

Deregulation of mini-chromosome maintenance (MCM) proteins is associated with genomic instability and cancer. MCM complexes are recruited to replication origins for genome duplication. Paradoxically, MCM proteins are in excess than the number of origins and are associated with chromatin regions away...

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Detalles Bibliográficos
Autores principales: Slaymaker, Ian M., Fu, Yang, Toso, Daniel B., Ranatunga, Nimna, Brewster, Aaron, Forsburg, Susan L., Zhou, Z. Hong, Chen, Xiaojiang S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597688/
https://www.ncbi.nlm.nih.gov/pubmed/23361460
http://dx.doi.org/10.1093/nar/gkt022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597688/
https://www.ncbi.nlm.nih.gov/pubmed/23361460
http://dx.doi.org/10.1093/nar/gkt022

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