Identification of a novel human mitochondrial endo-/exonuclease Ddk1/c20orf72 necessary for maintenance of proper 7S DNA levels

Although the human mitochondrial genome has been investigated for several decades, the proteins responsible for its replication and expression, especially nucleolytic enzymes, are poorly described. Here, we characterized a novel putative PD-(D/E)XK nuclease encoded by the human C20orf72 gene named D...

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Detalles Bibliográficos
Autores principales: Szczesny, Roman J., Hejnowicz, Monika S., Steczkiewicz, Kamil, Muszewska, Anna, Borowski, Lukasz S., Ginalski, Krzysztof, Dziembowski, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597694/
https://www.ncbi.nlm.nih.gov/pubmed/23358826
http://dx.doi.org/10.1093/nar/gkt029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597694/
https://www.ncbi.nlm.nih.gov/pubmed/23358826
http://dx.doi.org/10.1093/nar/gkt029

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