Differential roles for MBD2 and MBD3 at methylated CpG islands, active promoters and binding to exon sequences

The heterogeneous collection of nucleosome remodelling and deacetylation (NuRD) complexes can be grouped into the MBD2- or MBD3-containing complexes MBD2–NuRD and MBD3–NuRD. MBD2 is known to bind to methylated CpG sequences in vitro in contrast to MBD3. Although functional differences have been desc...

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Detalles Bibliográficos
Autores principales: Günther, Katharina, Rust, Mareike, Leers, Joerg, Boettger, Thomas, Scharfe, Maren, Jarek, Michael, Bartkuhn, Marek, Renkawitz, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597697/
https://www.ncbi.nlm.nih.gov/pubmed/23361464
http://dx.doi.org/10.1093/nar/gkt035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597697/
https://www.ncbi.nlm.nih.gov/pubmed/23361464
http://dx.doi.org/10.1093/nar/gkt035

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