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Structural insights into RISC assembly facilitated by dsRNA-binding domains of human RNA helicase A (DHX9)
Intensive research interest has focused on small RNA-processing machinery and the RNA-induced silencing complex (RISC), key cellular machines in RNAi pathways. However, the structural mechanism regarding RISC assembly, the primary step linking small RNA processing and RNA-mediated gene silencing, is...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597700/ https://www.ncbi.nlm.nih.gov/pubmed/23361462 http://dx.doi.org/10.1093/nar/gkt042 |