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Structural insights into RISC assembly facilitated by dsRNA-binding domains of human RNA helicase A (DHX9)

Intensive research interest has focused on small RNA-processing machinery and the RNA-induced silencing complex (RISC), key cellular machines in RNAi pathways. However, the structural mechanism regarding RISC assembly, the primary step linking small RNA processing and RNA-mediated gene silencing, is...

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Detalles Bibliográficos
Autores principales: Fu, Qinqin, Yuan, Y. Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597700/
https://www.ncbi.nlm.nih.gov/pubmed/23361462
http://dx.doi.org/10.1093/nar/gkt042