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Structural Insights into the Mechanism of Phosphoregulation of the Retinoblastoma Protein
The retinoblastoma susceptibility protein RB1 is a key regulator of cell proliferation and fate. RB1 operates through nucleating the formation of multi-component protein complexes involved in the regulation of gene transcription, chromatin structure and protein stability. Phosphorylation of RB1 by c...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597711/ https://www.ncbi.nlm.nih.gov/pubmed/23516486 http://dx.doi.org/10.1371/journal.pone.0058463 |