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Structural Insights into the Mechanism of Phosphoregulation of the Retinoblastoma Protein

The retinoblastoma susceptibility protein RB1 is a key regulator of cell proliferation and fate. RB1 operates through nucleating the formation of multi-component protein complexes involved in the regulation of gene transcription, chromatin structure and protein stability. Phosphorylation of RB1 by c...

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Detalles Bibliográficos
Autores principales: Lamber, Ekaterina P., Beuron, Fabienne, Morris, Edward P., Svergun, Dmitri I., Mittnacht, Sibylle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597711/
https://www.ncbi.nlm.nih.gov/pubmed/23516486
http://dx.doi.org/10.1371/journal.pone.0058463