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Mapping the Interactions of Dengue Virus NS1 Protein with Human Liver Proteins Using a Yeast Two-Hybrid System: Identification of C1q as an Interacting Partner

Dengue constitutes a global health concern. The clinical manifestation of this disease varies from mild febrile illness to severe hemorrhage and/or fatal hypovolemic shock. Flavivirus nonstructural protein 1 (NS1) is a secreted glycoprotein that is displayed on the surface of infected cells but is a...

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Detalles Bibliográficos
Autores principales: Silva, Emiliana M., Conde, Jonas N., Allonso, Diego, Nogueira, Mauricio L., Mohana-Borges, Ronaldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597719/
https://www.ncbi.nlm.nih.gov/pubmed/23516407
http://dx.doi.org/10.1371/journal.pone.0057514