Beta-Elemene Blocks Epithelial-Mesenchymal Transition in Human Breast Cancer Cell Line MCF-7 through Smad3-Mediated Down-Regulation of Nuclear Transcription Factors

Epithelial-mesenchymal transition (EMT) is the first step required for breast cancer to initiate metastasis. However, the potential of drugs to block and reverse the EMT process are not well explored. In the present study, we investigated the inhibitory effect of beta-elemene (ELE), an active compon...

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Detalles Bibliográficos
Autores principales: Zhang, Xian, Li, Yinghua, Zhang, Yang, Song, Jincheng, Wang, Qimin, Zheng, Luping, Liu, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597725/
https://www.ncbi.nlm.nih.gov/pubmed/23516540
http://dx.doi.org/10.1371/journal.pone.0058719

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597725/
https://www.ncbi.nlm.nih.gov/pubmed/23516540
http://dx.doi.org/10.1371/journal.pone.0058719

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