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Association between UGT1A1*28 Polymorphisms and Clinical Outcomes of Irinotecan-Based Chemotherapies in Colorectal Cancer: A Meta-Analysis in Caucasians

BACKGROUND: Whether UGT1A1*28 genotype is associated with clinical outcomes of irinotecan (IRI)-based chemotherapy in Colorectal cancer (CRC) is an important gap in existing knowledge to inform clinical utility. Published data on the association between UGT1A1*28 gene polymorphisms and clinical outc...

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Detalles Bibliográficos
Autores principales: Liu, Xiang, Cheng, Dangxiao, Kuang, Qin, Liu, Geoffrey, Xu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597733/
https://www.ncbi.nlm.nih.gov/pubmed/23516488
http://dx.doi.org/10.1371/journal.pone.0058489