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STAT3 mediates resistance of CD44(+)CD24(−/low) breast cancer stem cells to tamoxifen in vitro
We sought to determine whether STAT3 mediated tamoxifen resistance of breast cancer stem cells in vitro. The capacities for mammosphere formation and STAT3 expression of CD44(+)CD24(−/low) MCF-7 and MCF-7 were observed. The CD44(+)CD24(−/low) subpopulation ratio and its sensitivity to adriamycin wer...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Editorial Department of Journal of Biomedical Research
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597778/ https://www.ncbi.nlm.nih.gov/pubmed/23554768 http://dx.doi.org/10.7555/JBR.26.20110050 |