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STAT3 mediates resistance of CD44(+)CD24(−/low) breast cancer stem cells to tamoxifen in vitro

We sought to determine whether STAT3 mediated tamoxifen resistance of breast cancer stem cells in vitro. The capacities for mammosphere formation and STAT3 expression of CD44(+)CD24(−/low) MCF-7 and MCF-7 were observed. The CD44(+)CD24(−/low) subpopulation ratio and its sensitivity to adriamycin wer...

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Detalles Bibliográficos
Autores principales:	Wang, Xiaoyan, Wang, Guozhu, Zhao, Yi, Liu, Xiaoan, Ding, Qiang, Shi, Jingping, Ding, Yin, Wang, Shui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Editorial Department of Journal of Biomedical Research 2012
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597778/ https://www.ncbi.nlm.nih.gov/pubmed/23554768 http://dx.doi.org/10.7555/JBR.26.20110050

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