Structural Basis for Cul3 Protein Assembly with the BTB-Kelch Family of E3 Ubiquitin Ligases

Cullin-RING ligases are multisubunit E3 ubiquitin ligases that recruit substrate-specific adaptors to catalyze protein ubiquitylation. Cul3-based Cullin-RING ligases are uniquely associated with BTB adaptors that incorporate homodimerization, Cul3 assembly, and substrate recognition into a single mu...

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Detalles Bibliográficos
Autores principales: Canning, Peter, Cooper, Christopher D. O., Krojer, Tobias, Murray, James W., Pike, Ashley C. W., Chaikuad, Apirat, Keates, Tracy, Thangaratnarajah, Chancievan, Hojzan, Viktorija, Marsden, Brian D., Gileadi, Opher, Knapp, Stefan, von Delft, Frank, Bullock, Alex N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Protein Structure and Folding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597819/
https://www.ncbi.nlm.nih.gov/pubmed/23349464
http://dx.doi.org/10.1074/jbc.M112.437996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597819/
https://www.ncbi.nlm.nih.gov/pubmed/23349464
http://dx.doi.org/10.1074/jbc.M112.437996

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