SIRT1 and SIRT2: emerging targets in neurodegeneration

Sirtuins are NAD-dependent protein deacetylases known to have protective effects against age-related diseases such as cancer, diabetes, cardiovascular and neurodegenerative diseases. In mammals, there are seven sirtuins (SIRT1-7), which display diversity in subcellular localization and function. Whi...

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Detalles Bibliográficos
Autores principales: Donmez, Gizem, Outeiro, Tiago F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2013
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598076/
https://www.ncbi.nlm.nih.gov/pubmed/23417962
http://dx.doi.org/10.1002/emmm.201302451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598076/
https://www.ncbi.nlm.nih.gov/pubmed/23417962
http://dx.doi.org/10.1002/emmm.201302451

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