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SIRT1 and SIRT2: emerging targets in neurodegeneration
Sirtuins are NAD-dependent protein deacetylases known to have protective effects against age-related diseases such as cancer, diabetes, cardiovascular and neurodegenerative diseases. In mammals, there are seven sirtuins (SIRT1-7), which display diversity in subcellular localization and function. Whi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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WILEY-VCH Verlag
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598076/ https://www.ncbi.nlm.nih.gov/pubmed/23417962 http://dx.doi.org/10.1002/emmm.201302451 |