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Reactive astrocytes promote the metastatic growth of breast cancer stem-like cells by activating Notch signalling in brain

Brain metastasis of breast cancer profoundly affects the cognitive and sensory functions as well as morbidity of patients, and the 1 year survival rate among these patients remains less than 20%. However, the pathological mechanism of brain metastasis is as yet poorly understood. In this report, we...

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Detalles Bibliográficos
Autores principales: Xing, Fei, Kobayashi, Aya, Okuda, Hiroshi, Watabe, Misako, Pai, Sudha K, Pandey, Puspa R, Hirota, Shigeru, Wilber, Andrew, Mo, Yin-Yuan, Moore, Brian E, Liu, Wen, Fukuda, Koji, Iiizumi, Megumi, Sharma, Sambad, Liu, Yin, Wu, Kerui, Peralta, Elizabeth, Watabe, Kounosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598079/
https://www.ncbi.nlm.nih.gov/pubmed/23495140
http://dx.doi.org/10.1002/emmm.201201623