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Leflunomide inhibits the apoptosis of human embryonic lung fibroblasts infected by human cytomegalovirus

BACKGROUND: The immunomodulatory drug leflunomide (LEF) is frequently used for treating human cytomegalovirus (HCMV), but its antiviral mechanism is still unclear. In this study,we therefore investigated the effects of the active LEF metabolite A771726 on the HCMV lifecycle in human embryonic lung f...

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Detalles Bibliográficos
Autores principales: Qi, Ren, Hua-Song, Zeng, Xiao-Feng, Zeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598351/
https://www.ncbi.nlm.nih.gov/pubmed/23369524
http://dx.doi.org/10.1186/2047-783X-18-3