Short-Term Treatment With Rapamycin and Dietary Restriction Have Overlapping and Distinctive Effects in Young Mice

Because rapamycin, an inhibitor of the nutrient sensor mammalian target of rapamycin, and dietary restriction both increase life span of mice, it has been hypothesized that they act through similar mechanisms. To test this hypothesis, we compared various biological parameters in dietary restriction...

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Detalles Bibliográficos
Autores principales: Fok, Wilson C., Zhang, Yiqiang, Salmon, Adam B., Bhattacharya, Arunabh, Gunda, Rakesh, Jones, Dean, Ward, Walter, Fisher, Kathleen, Richardson, Arlan, Pérez, Viviana I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598360/
https://www.ncbi.nlm.nih.gov/pubmed/22570137
http://dx.doi.org/10.1093/gerona/gls127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598360/
https://www.ncbi.nlm.nih.gov/pubmed/22570137
http://dx.doi.org/10.1093/gerona/gls127

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