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Short-Term Treatment With Rapamycin and Dietary Restriction Have Overlapping and Distinctive Effects in Young Mice
Because rapamycin, an inhibitor of the nutrient sensor mammalian target of rapamycin, and dietary restriction both increase life span of mice, it has been hypothesized that they act through similar mechanisms. To test this hypothesis, we compared various biological parameters in dietary restriction...
Autores principales: | Fok, Wilson C., Zhang, Yiqiang, Salmon, Adam B., Bhattacharya, Arunabh, Gunda, Rakesh, Jones, Dean, Ward, Walter, Fisher, Kathleen, Richardson, Arlan, Pérez, Viviana I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598360/ https://www.ncbi.nlm.nih.gov/pubmed/22570137 http://dx.doi.org/10.1093/gerona/gls127 |
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