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Treatment with an anti-CD11d integrin antibody reduces neuroinflammation and improves outcome in a rat model of repeated concussion

BACKGROUND: Concussions account for the majority of traumatic brain injuries (TBI) and can result in cumulative damage, neurodegeneration, and chronic neurological abnormalities. The underlying mechanisms of these detrimental effects remain poorly understood and there are presently no specific treat...

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Detalles Bibliográficos
Autores principales: Shultz, Sandy R, Bao, Feng, Weaver, Lynne C, Cain, Donald P, Brown, Arthur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598378/
https://www.ncbi.nlm.nih.gov/pubmed/23414334
http://dx.doi.org/10.1186/1742-2094-10-26