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Vax1/2 Genes Counteract Mitf-Induced Respecification of the Retinal Pigment Epithelium

During vertebrate eye development, the transcription factor MITF acts to promote the development of the retinal pigment epithelium (RPE). In embryos with Mitf mutations, the future RPE hyperproliferates and is respecified as retinal tissue but only in a small portion of the dorsal RPE. Using a serie...

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Detalles Bibliográficos
Autores principales: Ou, Jingxing, Bharti, Kapil, Nodari, Alessandro, Bertuzzi, Stefano, Arnheiter, Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598659/
https://www.ncbi.nlm.nih.gov/pubmed/23555005
http://dx.doi.org/10.1371/journal.pone.0059247