Cargando…
Vax1/2 Genes Counteract Mitf-Induced Respecification of the Retinal Pigment Epithelium
During vertebrate eye development, the transcription factor MITF acts to promote the development of the retinal pigment epithelium (RPE). In embryos with Mitf mutations, the future RPE hyperproliferates and is respecified as retinal tissue but only in a small portion of the dorsal RPE. Using a serie...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598659/ https://www.ncbi.nlm.nih.gov/pubmed/23555005 http://dx.doi.org/10.1371/journal.pone.0059247 |