Cargando…
Vax1/2 Genes Counteract Mitf-Induced Respecification of the Retinal Pigment Epithelium
During vertebrate eye development, the transcription factor MITF acts to promote the development of the retinal pigment epithelium (RPE). In embryos with Mitf mutations, the future RPE hyperproliferates and is respecified as retinal tissue but only in a small portion of the dorsal RPE. Using a serie...
Autores principales: | Ou, Jingxing, Bharti, Kapil, Nodari, Alessandro, Bertuzzi, Stefano, Arnheiter, Heinz |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598659/ https://www.ncbi.nlm.nih.gov/pubmed/23555005 http://dx.doi.org/10.1371/journal.pone.0059247 |
Ejemplares similares
-
A Regulatory Loop Involving PAX6, MITF, and WNT Signaling Controls Retinal Pigment Epithelium Development
por: Bharti, Kapil, et al.
Publicado: (2012) -
PAX6 Regulates Melanogenesis in the Retinal Pigmented Epithelium through Feed-Forward Regulatory Interactions with MITF
por: Raviv, Shaul, et al.
Publicado: (2014) -
Partial Rescue of Ocular Pigment Cells and Structure by Inducible Ectopic Expression of Mitf-M in MITF-Deficient Mice
por: Michael, Helen T., et al.
Publicado: (2018) -
MITF—the first 25 years
por: Goding, Colin R., et al.
Publicado: (2019) -
Otx but Not Mitf Transcription Factors Are Required for Zebrafish Retinal Pigment Epithelium Development
por: Lane, Brandon M., et al.
Publicado: (2012)