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Expression and Secretion of Human Proinsulin-B10 from Mouse Salivary Glands: Implications for the Treatment of Type I Diabetes Mellitus

Adenovirus (Ad) mediated expression of therapeutic proteins from salivary glands can result in the delivery of biologically active proteins into the circulation where they impart their physiological function. In recent years, Ad vector delivery to salivary glands (SGs) has emerged as a viable option...

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Detalles Bibliográficos
Autores principales: Rowzee, Anne M., Perez-Riveros, Paola J., Zheng, Changyu, Krygowski, Sarah, Baum, Bruce J., Cawley, Niamh X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598661/
https://www.ncbi.nlm.nih.gov/pubmed/23554999
http://dx.doi.org/10.1371/journal.pone.0059222