MYCN Transgenic Zebrafish Model with the Characterization of Acute Myeloid Leukemia and Altered Hematopoiesis

BACKGROUND: Amplification of MYCN (N-Myc) oncogene has been reported as a frequent event and a poor prognostic marker in human acute myeloid leukemia (AML). The molecular mechanisms and transcriptional networks by which MYCN exerts its influence in AML are largely unknown. METHODOLOGY/PRINCIPAL FIND...

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Detalles Bibliográficos
Autores principales: Shen, Li-Jing, Chen, Fang-Yuan, Zhang, Yong, Cao, Lan-Fang, Kuang, Ying, Zhong, Min, Wang, Ting, Zhong, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598662/
https://www.ncbi.nlm.nih.gov/pubmed/23554972
http://dx.doi.org/10.1371/journal.pone.0059070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598662/
https://www.ncbi.nlm.nih.gov/pubmed/23554972
http://dx.doi.org/10.1371/journal.pone.0059070

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