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Immunization with Recombinant Prion Protein Leads to Partial Protection in a Murine Model of TSEs through a Novel Mechanism

Transmissible spongiform encephalopathies are neurodegenerative diseases, which despite fervent research remain incurable. Immunization approaches have shown great potential at providing protection, however tolerance effects hamper active immunization protocols. In this study we evaluated the antige...

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Detalles Bibliográficos
Autores principales: Xanthopoulos, Konstantinos, Lagoudaki, Rosa, Kontana, Anastasia, Kyratsous, Christos, Panagiotidis, Christos, Grigoriadis, Nikolaos, Yiangou, Minas, Sklaviadis, Theodoros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598700/
https://www.ncbi.nlm.nih.gov/pubmed/23554984
http://dx.doi.org/10.1371/journal.pone.0059143