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Immunization with Recombinant Prion Protein Leads to Partial Protection in a Murine Model of TSEs through a Novel Mechanism
Transmissible spongiform encephalopathies are neurodegenerative diseases, which despite fervent research remain incurable. Immunization approaches have shown great potential at providing protection, however tolerance effects hamper active immunization protocols. In this study we evaluated the antige...
Autores principales: | Xanthopoulos, Konstantinos, Lagoudaki, Rosa, Kontana, Anastasia, Kyratsous, Christos, Panagiotidis, Christos, Grigoriadis, Nikolaos, Yiangou, Minas, Sklaviadis, Theodoros |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598700/ https://www.ncbi.nlm.nih.gov/pubmed/23554984 http://dx.doi.org/10.1371/journal.pone.0059143 |
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