Cargando…

Improving stability and understandability of genotype-phenotype mapping in Saccharomyces using regularized variable selection in L-PLS regression

BACKGROUND: Multivariate approaches have been successfully applied to genome wide association studies. Recently, a Partial Least Squares (PLS) based approach was introduced for mapping yeast genotype-phenotype relations, where background information such as gene function classification, gene dispens...

Descripción completa

Detalles Bibliográficos
Autores principales: Mehmood, Tahir, Warringer, Jonas, Snipen, Lars, Sæbø, Solve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598729/
https://www.ncbi.nlm.nih.gov/pubmed/23216988
http://dx.doi.org/10.1186/1471-2105-13-327