Transposon activation mutagenesis as a screening tool for identifying resistance to cancer therapeutics

BACKGROUND: The development of resistance to chemotherapies represents a significant barrier to successful cancer treatment. Resistance mechanisms are complex, can involve diverse and often unexpected cellular processes, and can vary with both the underlying genetic lesion and the origin or type of...

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Detalles Bibliográficos
Autores principales: Chen, Li, Stuart, Lynda, Ohsumi, Toshiro K, Burgess, Shawn, Varshney, Gaurav K, Dastur, Anahita, Borowsky, Mark, Benes, Cyril, Lacy-Hulbert, Adam, Schmidt, Emmett V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598783/
https://www.ncbi.nlm.nih.gov/pubmed/23442791
http://dx.doi.org/10.1186/1471-2407-13-93

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598783/
https://www.ncbi.nlm.nih.gov/pubmed/23442791
http://dx.doi.org/10.1186/1471-2407-13-93

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