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Transposon activation mutagenesis as a screening tool for identifying resistance to cancer therapeutics
BACKGROUND: The development of resistance to chemotherapies represents a significant barrier to successful cancer treatment. Resistance mechanisms are complex, can involve diverse and often unexpected cellular processes, and can vary with both the underlying genetic lesion and the origin or type of...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598783/ https://www.ncbi.nlm.nih.gov/pubmed/23442791 http://dx.doi.org/10.1186/1471-2407-13-93 |