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Calcium Induced Regulation of Skeletal Troponin — Computational Insights from Molecular Dynamics Simulations

The interaction between calcium and the regulatory site(s) of striated muscle regulatory protein troponin switches on and off muscle contraction. In skeletal troponin binding of calcium to sites I and II of the TnC subunit results in a set of structural changes in the troponin complex, displaces tro...

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Detalles Bibliográficos
Autores principales: Genchev, Georgi Z., Kobayashi, Tomoyoshi, Lu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598806/
https://www.ncbi.nlm.nih.gov/pubmed/23554884
http://dx.doi.org/10.1371/journal.pone.0058313