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Calcium Induced Regulation of Skeletal Troponin — Computational Insights from Molecular Dynamics Simulations
The interaction between calcium and the regulatory site(s) of striated muscle regulatory protein troponin switches on and off muscle contraction. In skeletal troponin binding of calcium to sites I and II of the TnC subunit results in a set of structural changes in the troponin complex, displaces tro...
Autores principales: | Genchev, Georgi Z., Kobayashi, Tomoyoshi, Lu, Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598806/ https://www.ncbi.nlm.nih.gov/pubmed/23554884 http://dx.doi.org/10.1371/journal.pone.0058313 |
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