Spry1 and Spry4 Differentially Regulate Human Aortic Smooth Muscle Cell Phenotype via Akt/FoxO/Myocardin Signaling

BACKGROUND: Changes in the vascular smooth muscle cell (VSMC) contractile phenotype occur in pathological states such as restenosis and atherosclerosis. Multiple cytokines, signaling through receptor tyrosine kinases (RTK) and PI3K/Akt and MAPK/ERK pathways, regulate these phenotypic transitions. Th...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Xuehui, Gong, Yan, Tang, Yuefeng, Li, Hongfang, He, Qing, Gower, Lindsey, Liaw, Lucy, Friesel, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598808/
https://www.ncbi.nlm.nih.gov/pubmed/23554919
http://dx.doi.org/10.1371/journal.pone.0058746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598808/
https://www.ncbi.nlm.nih.gov/pubmed/23554919
http://dx.doi.org/10.1371/journal.pone.0058746

Ejemplares similares