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Posttranslational modifications and secretion efficiency of immunogenic hepatitis B virus L protein deletion variants

BACKGROUND: Subviral particles of hepatitis B virus (HBV) composed of L protein deletion variants with the 48 N-terminal amino acids of preS joined to the N-terminus of S protein (1-48preS/S) induced broadly neutralizing antibodies after immunization of mice with a Semliki Forest virus vector. A pra...

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Detalles Bibliográficos
Autores principales: Niedre-Otomere, Baiba, Bogdanova, Ance, Bruvere, Ruta, Ose, Velta, Gerlich, Wolfram H, Pumpens, Paul, Glebe, Dieter, Kozlovska, Tatjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598826/
https://www.ncbi.nlm.nih.gov/pubmed/23442390
http://dx.doi.org/10.1186/1743-422X-10-63