The Src-Family Kinase Inhibitor PP2 Rescues Inducible Differentiation Events in Emergent Retinoic Acid-Resistant Myeloblastic Leukemia Cells

Retinoic acid is an embryonic morphogen and dietary factor that demonstrates chemotherapeutic efficacy in inducing maturation in leukemia cells. Using HL60 model human myeloid leukemia cells, where all-trans retinoic acid (RA) induces granulocytic differentiation, we developed two emergent RA-resist...

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Detalles Bibliográficos
Autores principales: Jensen, Holly A., Styskal, Lauren E., Tasseff, Ryan, Bunaciu, Rodica P., Congleton, Johanna, Varner, Jeffrey D., Yen, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598855/
https://www.ncbi.nlm.nih.gov/pubmed/23554907
http://dx.doi.org/10.1371/journal.pone.0058621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598855/
https://www.ncbi.nlm.nih.gov/pubmed/23554907
http://dx.doi.org/10.1371/journal.pone.0058621

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