Anti-Analgesic Effect of the Mu/Delta Opioid Receptor Heteromer Revealed by Ligand-Biased Antagonism

Delta (DOR) and mu opioid receptors (MOR) can complex as heteromers, conferring functional properties in agonist binding, signaling and trafficking that can differ markedly from their homomeric counterparts. Because of these differences, DOR/MOR heteromers may be a novel therapeutic target in the tr...

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Detalles Bibliográficos
Autores principales: Milan-Lobo, Laura, Enquist, Johan, van Rijn, Richard M., Whistler, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598907/
https://www.ncbi.nlm.nih.gov/pubmed/23554887
http://dx.doi.org/10.1371/journal.pone.0058362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598907/
https://www.ncbi.nlm.nih.gov/pubmed/23554887
http://dx.doi.org/10.1371/journal.pone.0058362

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