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Distinct dedifferentiation processes affect caveolin-1 expression in hepatocytes

BACKGROUND: Dedifferentiation and loss of hepatocyte polarity during primary culture of hepatocytes are major drawbacks for metabolic analyses. As a prominent profibrotic cytokine and potent inducer of epithelial mesenchymal transition (EMT), TGF-β contributes to these processes in liver epithelial...

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Detalles Bibliográficos
Autores principales: Meyer, Christoph, Dzieran, Johanna, Liu, Yan, Schindler, Felizitas, Munker, Stefan, Müller, Alexandra, Coulouarn, Cédric, Dooley, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598962/
https://www.ncbi.nlm.nih.gov/pubmed/23339737
http://dx.doi.org/10.1186/1478-811X-11-6