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Anti-KIT designer T cells for the treatment of gastrointestinal stromal tumor

BACKGROUND: Imatinib mesylate is an effective treatment for metastatic gastrointestinal stromal tumor (GIST). However, most patients eventually develop resistance and there are few other treatment options. Immunotherapy using genetically modified or designer T cells (dTc) has gained increased attent...

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Detalles Bibliográficos
Autores principales: Katz, Steven C, Burga, Rachel A, Naheed, Seema, Licata, Lauren A, Thorn, Mitchell, Osgood, Doreen, Nguyen, Cang T, Espat, N Joseph, Fletcher, Jonathan A, Junghans, Richard P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599052/
https://www.ncbi.nlm.nih.gov/pubmed/23433424
http://dx.doi.org/10.1186/1479-5876-11-46