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Anti-KIT designer T cells for the treatment of gastrointestinal stromal tumor
BACKGROUND: Imatinib mesylate is an effective treatment for metastatic gastrointestinal stromal tumor (GIST). However, most patients eventually develop resistance and there are few other treatment options. Immunotherapy using genetically modified or designer T cells (dTc) has gained increased attent...
Autores principales: | Katz, Steven C, Burga, Rachel A, Naheed, Seema, Licata, Lauren A, Thorn, Mitchell, Osgood, Doreen, Nguyen, Cang T, Espat, N Joseph, Fletcher, Jonathan A, Junghans, Richard P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599052/ https://www.ncbi.nlm.nih.gov/pubmed/23433424 http://dx.doi.org/10.1186/1479-5876-11-46 |
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