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Prediction of conformational epitopes with the use of a knowledge-based energy function and geometrically related neighboring residue characteristics
BACKGROUND: A conformational epitope (CE) in an antigentic protein is composed of amino acid residues that are spatially near each other on the antigen's surface but are separated in sequence; CEs bind their complementary paratopes in B-cell receptors and/or antibodies. CE predication is used d...
Autores principales: | Lo, Ying-Tsang, Pai, Tun-Wen, Wu, Wei-Kuo, Chang, Hao-Teng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599093/ https://www.ncbi.nlm.nih.gov/pubmed/23514199 http://dx.doi.org/10.1186/1471-2105-14-S4-S3 |
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